Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Q7C_434Two-component sensor PilS; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (525 aa)    
Predicted Functional Partners:
Q7C_433
Type IV fimbriae expression regulatory protein PilR; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 
  0.991
Q7C_1695
RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.902
Q7C_117
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Biotin-requiring enzyme; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 0.835
Q7C_435
Hypothetical protein.
       0.830
Q7C_1764
Twitching motility protein PilG; PFAM: Response regulator receiver domain.
  
   0.811
Q7C_1765
Twitching motility protein PilH; PFAM: Response regulator receiver domain.
  
   0.791
Q7C_1768
Signal transduction histidine kinase CheA; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain.
 
 
 
 0.753
Q7C_646
PFAM: Protein of unknown function DUF58.
  
     0.691
Q7C_2689
Type IV pilus biogenesis protein PilZ; PFAM: PilZ domain.
  
     0.690
Q7C_1786
PFAM: Pilus assembly protein, PilP.
  
     0.678
Your Current Organism:
Methylophaga frappieri
NCBI taxonomy Id: 754477
Other names: ATCC BAA-2434, DSM 25690, M. frappieri, Methylophaga frappieri Villeneuve et al. 2013, Methylophaga sp. JAM7, strain JAM7
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