STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (317 aa)    
Predicted Functional Partners:
KXB68532.1
CRISPR-associated endoribonuclease Cas2; KEGG: aar:Acear_1599 1.8e-21 DNA polymerase III catalytic subunit, PolC type K03763; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.999
KXB68538.1
CRISPR system CASCADE complex protein CasA; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.971
KXB68534.1
CRISPR system CASCADE complex protein CasE; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.969
KXB68535.1
CRISPR system CASCADE complex protein CasD; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.969
KXB68536.1
CRISPR system CASCADE complex protein CasC.
 
  
 0.969
KXB68539.1
CRISPR-associated helicase Cas3; KEGG: ttn:TTX_1433 7.1e-05 lhr; large helicase-like protein K03724.
 
  
 0.966
KXB68537.1
CRISPR system CASCADE complex protein CasB.
 
  
 0.964
KXB68540.1
Macro domain protein; KEGG: hhd:HBHAL_5025 5.1e-38 ymdB; O-acetyl-ADP-ribose deacetylase.
       0.736
KXB67040.1
DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.696
KXB68541.1
Arylsulfatase; KEGG: bmd:BMD_0202 1.2e-30 sulfatase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.621
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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