| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB64999.1 | KXB65614.1 | HMPREF1863_01505 | HMPREF1863_01342 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | 0.813 |
| KXB64999.1 | KXB68356.1 | HMPREF1863_01505 | HMPREF1863_00067 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.435 |
| KXB64999.1 | guaA | HMPREF1863_01505 | HMPREF1863_00031 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.950 |
| KXB64999.1 | purD | HMPREF1863_01505 | HMPREF1863_00949 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: faa:HMPREF0389_00494 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family. | 0.590 |
| KXB64999.1 | purH | HMPREF1863_01505 | HMPREF1863_00950 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: faa:HMPREF0389_00495 7.9e-168 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.569 |
| KXB65614.1 | KXB64999.1 | HMPREF1863_01342 | HMPREF1863_01505 | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.813 |
| KXB65614.1 | KXB68356.1 | HMPREF1863_01342 | HMPREF1863_00067 | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | Magnesium transporter; Acts as a magnesium transporter. | 0.794 |
| KXB65614.1 | guaA | HMPREF1863_01342 | HMPREF1863_00031 | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.929 |
| KXB65614.1 | purH | HMPREF1863_01342 | HMPREF1863_00950 | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | KEGG: faa:HMPREF0389_00495 7.9e-168 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.782 |
| KXB68354.1 | KXB68355.1 | HMPREF1863_00065 | HMPREF1863_00066 | Hypothetical protein. | Hypothetical protein. | 0.429 |
| KXB68354.1 | KXB68356.1 | HMPREF1863_00065 | HMPREF1863_00067 | Hypothetical protein. | Magnesium transporter; Acts as a magnesium transporter. | 0.565 |
| KXB68355.1 | KXB68354.1 | HMPREF1863_00066 | HMPREF1863_00065 | Hypothetical protein. | Hypothetical protein. | 0.429 |
| KXB68355.1 | KXB68356.1 | HMPREF1863_00066 | HMPREF1863_00067 | Hypothetical protein. | Magnesium transporter; Acts as a magnesium transporter. | 0.572 |
| KXB68356.1 | KXB64999.1 | HMPREF1863_00067 | HMPREF1863_01505 | Magnesium transporter; Acts as a magnesium transporter. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.435 |
| KXB68356.1 | KXB65614.1 | HMPREF1863_00067 | HMPREF1863_01342 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family. | 0.794 |
| KXB68356.1 | KXB68354.1 | HMPREF1863_00067 | HMPREF1863_00065 | Magnesium transporter; Acts as a magnesium transporter. | Hypothetical protein. | 0.565 |
| KXB68356.1 | KXB68355.1 | HMPREF1863_00067 | HMPREF1863_00066 | Magnesium transporter; Acts as a magnesium transporter. | Hypothetical protein. | 0.572 |
| KXB68356.1 | guaA | HMPREF1863_00067 | HMPREF1863_00031 | Magnesium transporter; Acts as a magnesium transporter. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.858 |
| KXB68356.1 | purD | HMPREF1863_00067 | HMPREF1863_00949 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: faa:HMPREF0389_00494 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family. | 0.452 |
| KXB68356.1 | purH | HMPREF1863_00067 | HMPREF1863_00950 | Magnesium transporter; Acts as a magnesium transporter. | KEGG: faa:HMPREF0389_00495 7.9e-168 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.435 |