STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (394 aa)    
Predicted Functional Partners:
KXB68444.1
Methionine synthase, vitamin-B12 independent; KEGG: fma:FMG_0388 5.2e-116 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
 0.958
KXB65647.1
KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.880
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
       0.800
KXB65645.1
KEGG: csh:Closa_2454 1.1e-58 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.784
KXB68180.1
Aminotransferase, class I/II; KEGG: cdc:CD196_1202 1.3e-110 aspartate aminotransferase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.97.
  
 0.772
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
  
 0.748
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.706
KXB68382.1
Hypothetical protein; KEGG: pva:Pvag_2959 6.0e-14 yhgH; amidophosphoribosyltransferase; Psort location: Cytoplasmic, score: 8.96.
       0.701
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
   0.625
KXB68380.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.613
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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