STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB68404.1KEGG: hor:Hore_19320 1.2e-43 thiH; thiamine biosynthesis protein ThiH K03150; Psort location: Cytoplasmic, score: 8.96. (388 aa)    
Predicted Functional Partners:
KXB68405.1
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.996
KXB68407.1
Thiamine biosynthesis protein ThiS.
 
 
  0.939
thiE-2
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.887
KXB68406.1
KEGG: clo:HMPREF0868_0736 1.7e-62 putative thiamine biosynthesis protein ThiF; K03148 sulfur carrier protein ThiS adenylyltransferase; Psort location: Cytoplasmic, score: 9.97.
 
    0.869
KXB67049.1
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: hor:Hore_19320 3.5e-110 thiH; thiamine biosynthesis protein ThiH K03150; Psort location: Cytoplasmic, score: 8.96.
  
  
 
0.789
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.766
thiE
Putative thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.687
KXB68285.1
STAS domain protein; KEGG: ava:Ava_0744 0.00014 anti-sigma-factor antagonist (STAS) and sugar transfersase.
  
    0.679
KXB65585.1
Stage II sporulation protein E; KEGG: ava:Ava_3723 8.2e-20 response regulator receiver (CheY) modulated serine phosphatase; Psort location: Cytoplasmic, score: 8.96.
   
    0.676
KXB68402.1
4Fe-4S binding domain protein; KEGG: hor:Hore_20730 4.1e-06 pyruvate ferredoxin oxidoreductase subunit delta K00171; Psort location: Cytoplasmic, score: 8.96.
       0.675
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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