| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB68024.1 | KXB68025.1 | HMPREF1863_00341 | HMPREF1863_00342 | 3-dehydroquinate synthase; KEGG: lrm:LRC_04080 4.4e-96 glycerol dehydrogenase; K00005 glycerol dehydrogenase; Psort location: Cytoplasmic, score: 8.96. | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.505 |
| KXB68024.1 | KXB68026.1 | HMPREF1863_00341 | HMPREF1863_00343 | 3-dehydroquinate synthase; KEGG: lrm:LRC_04080 4.4e-96 glycerol dehydrogenase; K00005 glycerol dehydrogenase; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.416 |
| KXB68025.1 | KXB68024.1 | HMPREF1863_00342 | HMPREF1863_00341 | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 3-dehydroquinate synthase; KEGG: lrm:LRC_04080 4.4e-96 glycerol dehydrogenase; K00005 glycerol dehydrogenase; Psort location: Cytoplasmic, score: 8.96. | 0.505 |
| KXB68025.1 | KXB68026.1 | HMPREF1863_00342 | HMPREF1863_00343 | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.598 |
| KXB68025.1 | KXB68027.1 | HMPREF1863_00342 | HMPREF1863_00344 | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | CorA-like protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.504 |
| KXB68025.1 | KXB68588.1 | HMPREF1863_00342 | HMPREF1863_00057 | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Thermonuclease family protein; KEGG: bmq:BMQ_2840 2.4e-33 thermonuclease K01174; Psort location: Cytoplasmic, score: 8.96. | 0.406 |
| KXB68025.1 | mprF-2 | HMPREF1863_00342 | HMPREF1863_00837 | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.533 |
| KXB68026.1 | KXB68024.1 | HMPREF1863_00343 | HMPREF1863_00341 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 3-dehydroquinate synthase; KEGG: lrm:LRC_04080 4.4e-96 glycerol dehydrogenase; K00005 glycerol dehydrogenase; Psort location: Cytoplasmic, score: 8.96. | 0.416 |
| KXB68026.1 | KXB68025.1 | HMPREF1863_00343 | HMPREF1863_00342 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.598 |
| KXB68026.1 | KXB68027.1 | HMPREF1863_00343 | HMPREF1863_00344 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | CorA-like protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.553 |
| KXB68027.1 | KXB68025.1 | HMPREF1863_00344 | HMPREF1863_00342 | CorA-like protein; Psort location: CytoplasmicMembrane, score: 9.82. | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.504 |
| KXB68027.1 | KXB68026.1 | HMPREF1863_00344 | HMPREF1863_00343 | CorA-like protein; Psort location: CytoplasmicMembrane, score: 9.82. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.553 |
| KXB68588.1 | KXB68025.1 | HMPREF1863_00057 | HMPREF1863_00342 | Thermonuclease family protein; KEGG: bmq:BMQ_2840 2.4e-33 thermonuclease K01174; Psort location: Cytoplasmic, score: 8.96. | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.406 |
| mprF-2 | KXB68025.1 | HMPREF1863_00837 | HMPREF1863_00342 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.533 |