STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (237 aa)    
Predicted Functional Partners:
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.950
KXB67081.1
Thymidine kinase; KEGG: fma:FMG_0715 7.4e-46 thymidine kinase; K00857 thymidine kinase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.938
KXB67306.1
ComE operon protein 2 domain protein; KEGG: apr:Apre_0433 3.5e-23 zinc-binding CMP/dCMP deaminase; K01493 dCMP deaminase.
    
 0.908
dut
Putative dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 
 0.892
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.880
purD
KEGG: faa:HMPREF0389_00494 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family.
  
    0.868
KXB68031.1
Hypothetical protein.
 
    0.853
KXB68032.1
Hypothetical protein.
 
    0.846
KXB65614.1
KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
  
  0.820
KXB68033.1
KEGG: mas:Mahau_0369 5.0e-21 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.818
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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