| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB65647.1 | KXB68019.1 | HMPREF1863_01376 | HMPREF1863_00336 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.905 |
| KXB65647.1 | KXB68020.1 | HMPREF1863_01376 | HMPREF1863_00337 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | 0.824 |
| KXB65647.1 | cysS | HMPREF1863_01376 | HMPREF1863_00381 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | cysteine--tRNA ligase; KEGG: fma:FMG_0415 5.7e-142 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.851 |
| KXB65647.1 | glyA | HMPREF1863_01376 | HMPREF1863_01684 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.886 |
| KXB65647.1 | leuS | HMPREF1863_01376 | HMPREF1863_00995 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | leucine--tRNA ligase; KEGG: aoe:Clos_2587 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.422 |
| KXB65647.1 | thyX | HMPREF1863_01376 | HMPREF1863_00383 | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.843 |
| KXB68019.1 | KXB65647.1 | HMPREF1863_00336 | HMPREF1863_01376 | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.905 |
| KXB68019.1 | KXB68020.1 | HMPREF1863_00336 | HMPREF1863_00337 | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| KXB68019.1 | cysS | HMPREF1863_00336 | HMPREF1863_00381 | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | cysteine--tRNA ligase; KEGG: fma:FMG_0415 5.7e-142 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.956 |
| KXB68019.1 | glyA | HMPREF1863_00336 | HMPREF1863_01684 | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.673 |
| KXB68020.1 | KXB65647.1 | HMPREF1863_00337 | HMPREF1863_01376 | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97. | 0.824 |
| KXB68020.1 | KXB68019.1 | HMPREF1863_00337 | HMPREF1863_00336 | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.999 |
| KXB68020.1 | cysS | HMPREF1863_00337 | HMPREF1863_00381 | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | cysteine--tRNA ligase; KEGG: fma:FMG_0415 5.7e-142 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.982 |
| KXB68020.1 | glyA | HMPREF1863_00337 | HMPREF1863_01684 | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.791 |
| KXB68020.1 | mrnC | HMPREF1863_00337 | HMPREF1863_00382 | KEGG: ate:Athe_2254 1.0e-48 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97. | RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.450 |
| KXB68062.1 | KXB68066.1 | HMPREF1863_00380 | HMPREF1863_00384 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | KEGG: cpe:CPE2424 1.5e-61 RNA methyltransferase, TrmH family, group 3; K03218 23S rRNA (guanosine2251-2'-O)-methyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.655 |
| KXB68062.1 | KXB68067.1 | HMPREF1863_00380 | HMPREF1863_00385 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.655 |
| KXB68062.1 | cysS | HMPREF1863_00380 | HMPREF1863_00381 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | cysteine--tRNA ligase; KEGG: fma:FMG_0415 5.7e-142 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.655 |
| KXB68062.1 | mrnC | HMPREF1863_00380 | HMPREF1863_00382 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.655 |
| KXB68062.1 | thyX | HMPREF1863_00380 | HMPREF1863_00383 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.655 |