STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
unguracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (218 aa)    
Predicted Functional Partners:
KXB68415.1
Exodeoxyribonuclease III; KEGG: ere:EUBREC_0501 9.5e-101 exodeoxyribonuclease; K01142 exodeoxyribonuclease III; Psort location: Cytoplasmic, score: 9.97.
   
 0.919
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 0.836
KXB68290.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.816
KXB67287.1
Hypothetical protein; KEGG: cro:ROD_32441 4.8e-09 esterase K06889.
       0.807
KXB67285.1
TrkA protein; KEGG: scp:HMPREF0833_11023 0.00018 ktrA; Trk family potassium (K+) transporter, NAD+ binding protein K03499; Psort location: Cytoplasmic, score: 8.96.
       0.764
KXB67284.1
Cation transport protein; KEGG: ssr:SALIVB_0283 8.2e-79 DNA polymerase IV K03498; Psort location: CytoplasmicMembrane, score: 10.00.
       0.761
KXB67283.1
Putative potassium transporter peripheral membrane component; KEGG: scp:HMPREF0833_11023 5.4e-66 ktrA; Trk family potassium (K+) transporter, NAD+ binding protein K03499; Psort location: CytoplasmicMembrane, score: 7.88.
       0.759
KXB67282.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.730
nfo
Apurinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
   
 
 0.604
KXB67288.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.589
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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