STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (286 aa)    
Predicted Functional Partners:
KXB67013.1
Threonine synthase; KEGG: med:MELS_1583 9.7e-115 threonine synthase; K01733 threonine synthase; Psort location: Cytoplasmic, score: 9.97.
 
 0.998
KXB68201.1
KEGG: cle:Clole_1610 9.7e-60 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
 0.997
KXB67215.1
Aspartate kinase; KEGG: cst:CLOST_1413 5.9e-108 aspartokinase K00928; Psort location: Cytoplasmic, score: 8.96; Belongs to the aspartokinase family.
 
 0.983
KXB65647.1
KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.950
purM
KEGG: faa:HMPREF0389_00497 9.7e-115 phosphoribosylformylglycinamidine cyclo-ligase; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97.
 
 
  
 0.938
KXB65607.1
KEGG: txy:Thexy_0012 5.6e-16 acetolactate synthase small subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.937
KXB68276.1
HAD hydrolase, family IB; KEGG: cbj:H04402_02837 8.4e-22 phosphoserine phosphatase.
  
 0.924
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.924
KXB68071.1
Beta-eliminating lyase; KEGG: dhd:Dhaf_1081 1.6e-68 threonine aldolase K01620; Psort location: Cytoplasmic, score: 8.96.
   
 0.906
KXB68019.1
KEGG: apr:Apre_0955 2.8e-78 cysteine synthase A; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 9.97; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.894
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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