STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mprF-2Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (841 aa)    
Predicted Functional Partners:
KXB67112.1
Hydrolase, alpha/beta domain protein; KEGG: efc:EFAU004_01231 2.5e-45 alpha/beta hydrolase; Psort location: Cytoplasmic, score: 9.26.
       0.809
lysS
lysine--tRNA ligase; KEGG: faa:HMPREF0389_00147 8.0e-175 lysine--tRNA ligase; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.719
KXB65567.1
KEGG: cby:CLM_2977 7.6e-28 group 2 family glycosyl transferase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.589
KXB67110.1
Hypothetical protein.
  
    0.576
KXB67417.1
Hypothetical protein; KEGG: mrs:Murru_0906 0.0020 phospholipase D; K06131 cardiolipin synthase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.535
KXB68025.1
Acyltransferase; KEGG: efu:HMPREF0351_12432 1.6e-66 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.533
KXB67113.1
4Fe-4S binding domain protein; KEGG: hpk:Hprae_1780 4.0e-125 ferredoxin hydrogenase.
       0.529
KXB67208.1
Monogalactosyldiacylglycerol synthase protein; KEGG: cdl:CDR20291_1186 4.6e-37 cell wall biosynthesis protein; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 8.96.
    
 0.525
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
    
 0.525
KXB67203.1
Acyltransferase; KEGG: efc:EFAU004_02493 1.0e-40 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.506
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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