STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdRPutative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. (106 aa)    
Predicted Functional Partners:
asnS
asparagine--tRNA ligase; KEGG: cth:Cthe_0070 1.3e-176 asnC; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00.
       0.813
KXB66615.1
ATPase, AAA family; KEGG: atm:ANT_00900 6.8e-107 putative ATPase K07478; Psort location: Cytoplasmic, score: 9.97.
       0.813
leuS
leucine--tRNA ligase; KEGG: aoe:Clos_2587 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.806
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.639
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.629
KXB67096.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.603
KXB66611.1
Putative sporulation integral membrane protein YtvI; KEGG: tbd:Tbd_2668 7.6e-29 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: CytoplasmicMembrane, score: 10.00.
       0.595
KXB66612.1
Putative HTH-type transcriptional regulator CymR; KEGG: hmc:HYPMC_1094 5.9e-17 Rrf2 family transcriptional regulator K04487; Psort location: Cytoplasmic, score: 8.96.
       0.583
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.489
KXB66620.1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hip:CGSHiEE_06365 3.8e-49 murG; N-acetylglucosaminyl transferase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
  
    0.459
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.