STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (435 aa)    
Predicted Functional Partners:
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.992
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 0.990
KXB65033.1
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.0e-110 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97; Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.979
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
0.972
KXB66618.1
POTRA domain protein, FtsQ-type; Essential cell division protein.
  
  
 0.971
KXB66623.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: aoe:Clos_1373 8.6e-107 peptidoglycan glycosyltransferase K08384; Psort location: CytoplasmicMembrane, score: 9.82.
 
  
 0.961
KXB66620.1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hip:CGSHiEE_06365 3.8e-49 murG; N-acetylglucosaminyl transferase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
  
 0.957
KXB65371.1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 9.1e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.97.
 
 
0.945
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
  
 0.935
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.896
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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