STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
KXB65965.1Putative isocitrate dehydrogenase, NAD-dependent; KEGG: apr:Apre_1101 4.0e-118 isocitrate dehydrogenase K00030; Psort location: Cytoplasmic, score: 9.97. (334 aa)    
Predicted Functional Partners:
KXB65966.1
KEGG: apr:Apre_1102 8.0e-223 aconitate hydratase; K01681 aconitate hydratase 1; Psort location: Cytoplasmic, score: 9.97.
 0.983
KXB65964.1
KEGG: apr:Apre_1100 1.1e-131 citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
 
 0.967
KXB65607.1
KEGG: txy:Thexy_0012 5.6e-16 acetolactate synthase small subunit; K01653 acetolactate synthase I/III small subunit; Psort location: Cytoplasmic, score: 8.96.
  
 0.961
KXB65608.1
KEGG: bhy:BHWA1_01047 6.6e-148 acetolactate synthase large subunit; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.97.
 
 0.920
KXB65387.1
KEGG: txy:Thexy_1943 0. pyruvate ferredoxin/flavodoxin oxidoreductase K03737; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.911
KXB65227.1
KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.911
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.893
ilvD
Dihydroxy-acid dehydratase; KEGG: bpo:BP951000_0506 4.2e-201 livD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 9.97; Belongs to the IlvD/Edd family.
  
  
 0.850
KXB67014.1
Oxidoreductase NAD-binding domain protein; KEGG: cbb:CLD_1218 1.4e-92 ferredoxin-NADP reductase; K00528 ferredoxin--NADP+ reductase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.787
KXB67015.1
Glutamate synthase; KEGG: cbt:CLH_2956 6.8e-162 gltA; putative oxidoreductase; K00266 glutamate synthase (NADPH/NADH) small chain; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.787
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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