STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB65554.1Peptidase, S41 family; KEGG: mas:Mahau_1750 2.4e-72 carboxyl-terminal protease; K03797 carboxyl-terminal processing protease; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the peptidase S41A family. (387 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.748
KXB65555.1
Peptidase, M23 family; KEGG: npu:Npun_F4637 9.0e-41 peptidase M23B; Psort location: OuterMembrane, score: 8.28.
 
    0.748
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.732
KXB65556.1
Efflux ABC transporter, permease protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.604
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.604
KXB65087.1
RIP metalloprotease RseP; KEGG: toc:Toce_1250 2.1e-64 membrane-associated zinc metalloprotease; K11749 regulator of sigma E protease; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.595
KXB68046.1
Trypsin; KEGG: cst:CLOST_2551 4.2e-75 2-alkenal reductase K08070; Psort location: Periplasmic, score: 9.44.
    
 0.523
pheT
KEGG: amt:Amet_1640 2.9e-177 pheT; phenylalanyl-tRNA synthetase subunit beta K01890; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.487
KXB65551.1
Arginine ABC transporter, periplasmic arginine-binding protein ArtP family protein; KEGG: npu:Npun_F6325 2.4e-33 polar amino acid ABC transporter inner membrane subunit K02029:K02030; Psort location: Periplasmic, score: 10.00; Belongs to the bacterial solute-binding protein 3 family.
   
   0.458
KXB68357.1
Hypothetical protein; KEGG: smb:smi_0705 0. prtA; cell wall-associated serine proteinase.
  
   0.451
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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