STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB65630.1Pentapeptide repeat protein; KEGG: mar:MAE_53550 1.7e-05 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial. (202 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.874
KXB68458.1
Pyruvate kinase; KEGG: amt:Amet_4068 3.0e-145 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 9.97.
    
 0.682
KXB67335.1
D-proline reductase, PrdA proprotein; KEGG: cdl:CDR20291_3100 2.2e-69 hypothetical protein; K10795 D-proline reductase (dithiol) PrdD; Psort location: Cytoplasmic, score: 9.97.
  
     0.665
KXB67332.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
     0.657
KXB67325.1
Hypothetical protein; KEGG: aoe:Clos_0032 1.5e-56 D-proline reductase K10796; Psort location: Cytoplasmic, score: 9.26.
  
     0.656
KXB67331.1
KEGG: cdf:CD3244 1.7e-206 prdA; proline reductase subunit proprotein; K10793 D-proline reductase (dithiol) PrdA; Psort location: Cytoplasmic, score: 9.97.
  
     0.648
KXB67329.1
Hypothetical protein; KEGG: amt:Amet_0665 2.3e-29 D-proline reductase K10793; Psort location: Cytoplasmic, score: 9.97.
  
     0.640
KXB65614.1
KEGG: aoe:Clos_0920 9.9e-106 5'-nucleotidase domain-containing protein; K01081 5'-nucleotidase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
  
 
 0.640
KXB65059.1
LysM domain protein; KEGG: bsr:I33_1551 0.00026 endopeptidase LytF.
   
 
 0.628
KXB67333.1
KEGG: cbi:CLJ_B2705 1.3e-57 prdB; D-proline reductase, PrdB subunit K10794; Psort location: Cytoplasmic, score: 9.97.
  
     0.613
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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