STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (281 aa)    
Predicted Functional Partners:
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.935
KXB64999.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
  0.933
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.846
KXB65647.1
KEGG: csh:Closa_2452 9.0e-215 homocysteine S-methyltransferase; K00548 5-methyltetrahydrofolate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 9.97.
       0.812
purD
KEGG: faa:HMPREF0389_00494 0. phosphoribosylformylglycinamidine synthase; K01952 phosphoribosylformylglycinamidine synthase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family.
    
  0.809
KXB65641.1
SCP-like protein; KEGG: nth:Nther_1077 7.9e-10 N-acetylmuramoyl-L-alanine amidase K01448; Psort location: Cytoplasmic, score: 8.96.
 
     0.799
KXB65646.1
Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: cbj:H04402_01691 5.6e-16 methionine synthase activation domain; Psort location: Cytoplasmic, score: 8.96.
       0.777
KXB65642.1
Hypothetical protein.
       0.773
KXB65644.1
Glycosyltransferase, group 2 family protein; KEGG: ssa:SSA_0425 3.8e-58 glycosyltransferase; Psort location: CytoplasmicMembrane, score: 9.46.
       0.773
KXB65645.1
KEGG: csh:Closa_2454 1.1e-58 5,10-methylenetetrahydrofolate reductase K00297; Psort location: Cytoplasmic, score: 9.97.
       0.773
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.