| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB65321.1 | KXB65323.1 | HMPREF1863_01417 | HMPREF1863_01419 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.827 |
| KXB65321.1 | KXB65324.1 | HMPREF1863_01417 | HMPREF1863_01420 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.809 |
| KXB65321.1 | KXB68033.1 | HMPREF1863_01417 | HMPREF1863_00350 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | KEGG: mas:Mahau_0369 5.0e-21 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 8.96. | 0.735 |
| KXB65321.1 | KXB68181.1 | HMPREF1863_01417 | HMPREF1863_00202 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Putative DNA replication protein DnaC; KEGG: apb:SAR116_1558 0.00013 ATPase K02313; Psort location: Cytoplasmic, score: 8.96. | 0.970 |
| KXB65321.1 | dnaA | HMPREF1863_01417 | HMPREF1863_00314 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.901 |
| KXB65321.1 | dnaG | HMPREF1863_01417 | HMPREF1863_00704 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.990 |
| KXB65321.1 | dnaX | HMPREF1863_01417 | HMPREF1863_00686 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.758 |
| KXB65321.1 | rplI | HMPREF1863_01417 | HMPREF1863_01418 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.864 |
| KXB65321.1 | tuf | HMPREF1863_01417 | HMPREF1863_00190 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.778 |
| KXB65321.1 | uppP | HMPREF1863_01417 | HMPREF1863_01416 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.773 |
| KXB65323.1 | KXB65321.1 | HMPREF1863_01419 | HMPREF1863_01417 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.827 |
| KXB65323.1 | KXB65324.1 | HMPREF1863_01419 | HMPREF1863_01420 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.873 |
| KXB65323.1 | rplI | HMPREF1863_01419 | HMPREF1863_01418 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.848 |
| KXB65323.1 | uppP | HMPREF1863_01419 | HMPREF1863_01416 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.773 |
| KXB65324.1 | KXB65321.1 | HMPREF1863_01420 | HMPREF1863_01417 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.809 |
| KXB65324.1 | KXB65323.1 | HMPREF1863_01420 | HMPREF1863_01419 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.873 |
| KXB65324.1 | rplI | HMPREF1863_01420 | HMPREF1863_01418 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.913 |
| KXB65324.1 | tuf | HMPREF1863_01420 | HMPREF1863_00190 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.454 |
| KXB65324.1 | uppP | HMPREF1863_01420 | HMPREF1863_01416 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.768 |
| KXB68033.1 | KXB65321.1 | HMPREF1863_00350 | HMPREF1863_01417 | KEGG: mas:Mahau_0369 5.0e-21 DNA polymerase III subunit delta'; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 8.96. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.735 |