STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
KXB64901.1Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; KEGG: fma:FMG_1460 1.9e-109 pyridoxal biosynthesis lyase PdxS; K06215 pyridoxine biosynthesis protein; Psort location: Cytoplasmic, score: 8.96; Belongs to the PdxS/SNZ family. (285 aa)    
Predicted Functional Partners:
KXB67403.1
KEGG: paw:PAZ_c08620 5.3e-107 gap; glyceraldehyde-3-phosphate dehydrogenase K00134; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.823
KXB65571.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
  0.779
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
  0.774
tal
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
  0.760
KXB65972.1
Putative glucose-resistance amylase regulator; KEGG: apr:Apre_0881 1.2e-68 LacI family transcriptional regulator K02529; Psort location: Cytoplasmic, score: 9.97.
    
  0.657
KXB64902.1
KEGG: fnu:FN1462 9.7e-76 GntR family transcriptional regulator K00375; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.648
KXB68399.1
Phosphomethylpyrimidine kinase; KEGG: tte:TTE2235 1.8e-67 ThiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; K00941 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
    
 0.638
KXB67080.1
Kinase, PfkB family; KEGG: ova:OBV_10270 3.1e-38 pscK; pseudouridine kinase.
    
 0.594
KXB65106.1
KEGG: pjd:Pjdr2_3748 2.0e-59 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 9.97.
    
  0.544
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.508
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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