STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB64911.1RNA polymerase sigma factor, sigma-70 family; KEGG: edi:EDI_048910 0.0077 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 8.96. (205 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.768
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.758
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.652
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.651
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.471
KXB65108.1
Kinase domain protein; KEGG: tte:TTE1500 8.9e-105 Sps1; Serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; Psort location: CytoplasmicMembrane, score: 7.88.
   
 
 0.439
KXB64910.1
Hypothetical protein.
       0.429
KXB68357.1
Hypothetical protein; KEGG: smb:smi_0705 0. prtA; cell wall-associated serine proteinase.
    
  0.427
KXB68170.1
Repeat protein; KEGG: aag:AaeL_AAEL000109 1.3e-13 enolase-phosphatase e-1; K09880 enolase-phosphatase E1; Psort location: Periplasmic, score: 8.56.
    
  0.427
KXB67774.1
Hypothetical protein; KEGG: hhd:HBHAL_4444 1.1e-20 alkaline serine protease, subtilase family; Psort location: Periplasmic, score: 9.83.
    
  0.427
Your Current Organism:
Peptoniphilus coxii
NCBI taxonomy Id: 755172
Other names: ATCC BAA-2106, CCUG 59622, JCM 16892, P. coxii, Peptoniphilus coxii Citron et al. 2013, Peptoniphilus sp. RMA 16757, strain RMA 16757
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