STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ53080.1KEGG: cyh:Cyan8802_0033 hypothetical protein; SPTR: Putative uncharacterized protein. (274 aa)    
Predicted Functional Partners:
AFZ54056.1
Peptidoglycan-binding lysin domain protein; PFAM: LysM domain; InterPro IPR002482:IPR018392; KEGG: ana:all4476 hypothetical protein; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidoglycan-binding LysM.
   
    0.709
AFZ53079.1
PFAM: Uncharacterised protein family (UPF0104); COGs: COG0392 integral membrane protein; KEGG: cyc:PCC7424_1145 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.553
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.430
AFZ53665.1
PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR006691; KEGG: cyc:PCC7424_0929 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA topoisomerase, type IIA, subunit A/C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A/C-terminal; SPTR: DNA topoisomerase (ATP-hydrolyzing).
  
    0.430
Your Current Organism:
Cyanobacterium aponinum
NCBI taxonomy Id: 755178
Other names: C. aponinum PCC 10605, Cyanobacterium aponinum PCC 10605, Cyanobacterium sp. PCC 10605
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