STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBPFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); HAMAP: Glutathione synthetase, prokaryotic; InterPro IPR004215:IPR004218:IPR006284; KEGG: ter:Tery_4206 glutathione synthetase; PFAM: Prokaryotic glutathione synthetase, ATP-binding; Prokaryotic glutathione synthetase, N-terminal; PRIAM: Glutathione synthase; SPTR: Glutathione synthase; TIGRFAM: Glutathione synthetase, prokaryo [...] (321 aa)    
Predicted Functional Partners:
AFZ53366.1
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; COGs: COG0625 Glutathione S-transferase; InterPro IPR004045:IPR004046; KEGG: npu:Npun_F4735 glutathione S-transferase domain-containing protein; PFAM: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal; SPTR: Glutathione S-transferase-like protein.
 
  
 0.929
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.918
AFZ54707.1
Gamma-glutamyltransferase 1; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase; COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: hse:Hsero_1089 gamma-glutamyltranspeptidase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: Gamma-glutamyltranspeptidase.
     
 0.912
AFZ52871.1
Membrane alanyl aminopeptidase; PFAM: Peptidase family M1; COGs: COG0308 Aminopeptidase N; InterPro IPR004155:IPR014782; KEGG: cyc:PCC7424_4277 peptidase M1 membrane alanine aminopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal; PBS lyase HEAT-like repeat; PRIAM: Membrane alanyl aminopeptidase; SPTR: HEAT:Peptidase M1, membrane alanine aminopeptidase:PBS lyase HEAT-like repeat.
     
 0.903
AFZ54191.1
PFAM: MAPEG family; InterPro IPR001129; KEGG: cyc:PCC7424_0880 membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG); PFAM: Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein; SPTR: Membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG).
    
  0.903
AFZ52939.1
COGs: COG0625 Glutathione S-transferase; KEGG: cyc:PCC7424_4049 glutathione S-transferase domain protein; SPTR: Glutathione S-transferase domain protein.
    
 0.901
AFZ53934.1
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; COGs: COG0625 Glutathione S-transferase; InterPro IPR004045:IPR004046; KEGG: syp:SYNPCC7002_A0118 glutathione S-transferase; PFAM: Glutathione S-transferase, N-terminal; Glutathione S-transferase, C-terminal; SPTR: Glutathione S-transferase.
    
 0.901
AFZ54144.1
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
   
 0.891
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.802
AFZ53877.1
Glutaredoxin-like protein; PFAM: Glutaredoxin; TIGRFAM: monothiol glutaredoxin, Grx4 family; COGs: COG0278 Glutaredoxin-related protein; InterPro IPR004480:IPR002109; KEGG: syf:Synpcc7942_1145 glutaredoxin-like protein; PFAM: Glutaredoxin; SPTR: Promoter active E3; TIGRFAM: Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
     0.636
Your Current Organism:
Cyanobacterium aponinum
NCBI taxonomy Id: 755178
Other names: C. aponinum PCC 10605, Cyanobacterium aponinum PCC 10605, Cyanobacterium sp. PCC 10605
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