STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ55222.1Thiamine S protein; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal; InterPro IPR003749; KEGG: ter:Tery_4347 thiamineS; PFAM: ThiamineS; SPTR: ThiamineS. (89 aa)    
Predicted Functional Partners:
AFZ53937.1
PFAM: MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: cyt:cce_0706 molybdopterin (MPT) converting factor, subunit 2; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin (MPT) converting factor, subunit 2.
 
 0.997
AFZ54545.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901:IPR001763; KEGG: cyt:cce_2667 hypothetical protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; Rhodanese-like; SMART: Rhodanese-like; SPTR: Molybdopterin biosynthesis protein MoeB.
  
 0.981
AFZ54297.1
Molybdopterin synthase subunit MoaD; PFAM: ThiS family; InterPro IPR003749; KEGG: mar:MAE_17050 hypothetical protein; PFAM: ThiamineS; SPTR: Similar to Cter of sp|P74060|Y821_SYNY3 UPF0084 protein slr0821.
     
  0.900
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.810
thiG
Glycine oxidase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.795
AFZ53129.1
KEGG: cyt:cce_3225 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.702
AFZ54351.1
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.680
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.673
AFZ52406.1
Hypothetical protein; PFAM: Uncharacterised BCR, COG1649; KEGG: cyc:PCC7424_1578 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.672
AFZ54046.1
PFAM: Protein of unknown function (DUF790); COGs: COG3372 conserved hypothetical protein; InterPro IPR008508; KEGG: cyc:PCC7424_0826 protein of unknown function DUF790; PFAM: Protein of unknown function DUF790, endonuclease-like; SPTR: Putative uncharacterized protein.
  
     0.672
Your Current Organism:
Cyanobacterium aponinum
NCBI taxonomy Id: 755178
Other names: C. aponinum PCC 10605, Cyanobacterium aponinum PCC 10605, Cyanobacterium sp. PCC 10605
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