STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFZ55247.1Putative integral membrane sensor protein; PFAM: Bacterial signalling protein N terminal repeat; COGs: COG3300 MHYT domain (predicted integral membrane sensor domain); InterPro IPR005330; KEGG: bss:BSUW23_06885 putative sensor protein; PFAM: MHYT; SPTR: Putative sensor protein. (248 aa)    
Predicted Functional Partners:
AFZ52925.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; FHA domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000160:IPR000253:IPR001633:IPR 013767; KEGG: cyp:PCC8801_1348 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylat [...]
    
 0.935
AFZ53481.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR013655:IPR003018:IPR003661:IPR003594:IPR 001789:IPR000014:IPR001610; KEGG: ana:alr3120 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, [...]
 
    0.913
AFZ54028.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: cyh:Cyan8802_1611 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: GAF sensor signal transduction histidine kinase.
 
     0.913
AFZ55229.1
PFAM: EAL domain; GGDEF domain; FHA domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000253:IPR000160:IPR001633; KEGG: cyt:cce_4650 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Forkhead-associated; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: Diguanylate cyclase, predicted.
    
 0.913
AFZ52836.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003018:IPR001610:IPR003661:IPR 003594:IPR001789:IPR013655; KEGG: ava:Ava_4701 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bind [...]
 
    0.912
AFZ52973.1
PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001789:IPR001633; KEGG: cyh:Cyan8802_0849 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Response regulator receive [...]
    
 0.912
AFZ53247.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003018:IPR003661:IPR003594; KEGG: aci:ACIAD3176 putative sensory transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; SPTR: Putative uncharacterized protein.
 
     0.912
AFZ53388.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: cyc:PCC7424_2022 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SPTR: Putative Cyclic diguanylate [...]
    
 0.912
AFZ54004.1
PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: npu:Npun_F5361 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction respo [...]
 
    0.912
AFZ53470.1
Integral membrane sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; MASE1; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR007895:IPR003661:IPR003594:IPR001789; KEGG: syp:SYNPCC7002_A0867 two-component hybrid sensor and regulator; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; MASE1; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction response [...]
 
 
    0.910
Your Current Organism:
Cyanobacterium aponinum
NCBI taxonomy Id: 755178
Other names: C. aponinum PCC 10605, Cyanobacterium aponinum PCC 10605, Cyanobacterium sp. PCC 10605
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