node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ53505.1 | AFZ53847.1 | Cyan10605_1393 | Cyan10605_1744 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | 0.900 |
AFZ53505.1 | AFZ54446.1 | Cyan10605_1393 | Cyan10605_2363 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.924 |
AFZ53505.1 | AFZ55497.1 | Cyan10605_1393 | Cyan10605_3460 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyt:cce_2273 hypothetical protein; PFAM: Protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.900 |
AFZ53505.1 | ahcY | Cyan10605_1393 | Cyan10605_2324 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.816 |
AFZ53505.1 | asd | Cyan10605_1393 | Cyan10605_0019 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.977 |
AFZ53643.1 | AFZ53847.1 | Cyan10605_1534 | Cyan10605_1744 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | 0.802 |
AFZ53643.1 | AFZ54446.1 | Cyan10605_1534 | Cyan10605_2363 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.885 |
AFZ53643.1 | AFZ54981.1 | Cyan10605_1534 | Cyan10605_2919 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.912 |
AFZ53643.1 | AFZ55497.1 | Cyan10605_1534 | Cyan10605_3460 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyt:cce_2273 hypothetical protein; PFAM: Protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.803 |
AFZ53643.1 | ahcY | Cyan10605_1534 | Cyan10605_2324 | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.858 |
AFZ53847.1 | AFZ53505.1 | Cyan10605_1744 | Cyan10605_1393 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | 0.900 |
AFZ53847.1 | AFZ53643.1 | Cyan10605_1744 | Cyan10605_1534 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | 0.802 |
AFZ53847.1 | AFZ54446.1 | Cyan10605_1744 | Cyan10605_2363 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.922 |
AFZ53847.1 | AFZ54981.1 | Cyan10605_1744 | Cyan10605_2919 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: cyc:PCC7424_1502 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.802 |
AFZ53847.1 | AFZ55497.1 | Cyan10605_1744 | Cyan10605_3460 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | PFAM: Domain of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: cyt:cce_2273 hypothetical protein; PFAM: Protein of unknown function DUF39; SPTR: Putative uncharacterized protein. | 0.979 |
AFZ53847.1 | ahcY | Cyan10605_1744 | Cyan10605_2324 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.910 |
AFZ53847.1 | asd | Cyan10605_1744 | Cyan10605_0019 | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.900 |
AFZ54446.1 | AFZ53505.1 | Cyan10605_2363 | Cyan10605_1393 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: mar:MAE_45060 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase. | 0.924 |
AFZ54446.1 | AFZ53643.1 | Cyan10605_2363 | Cyan10605_1534 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyc:PCC7424_4638 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase. | 0.885 |
AFZ54446.1 | AFZ53847.1 | Cyan10605_2363 | Cyan10605_1744 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | NIL domain-containing protein; PFAM: NIL domain; InterPro IPR018449; KEGG: ava:Ava_0339 4Fe-4S ferredoxin, iron-sulfur binding; PFAM: NIL domain; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. | 0.922 |