STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA42209.1Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: gfo:GFO_2310 O-succinylbenzoate synthase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SPTR: Chloromuconate cycloisomerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoic acid (OSB) synthetase. (344 aa)    
Predicted Functional Partners:
AEA45351.1
O-succinylbenzoate--CoA ligase; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; KEGG: fps:FP1601 O-succinylbenzoate--CoA ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
 
 0.991
menA
1,4-dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.945
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.857
AEA42287.1
Chorismate binding domain-containing protein; COGs: COG1169 Isochorismate synthase; InterPro IPR015890; KEGG: zpr:ZPR_1714 isochorismate synthase; PFAM: Chorismate binding, C-terminal; SPTR: Isochorismate synthase; PFAM: chorismate binding enzyme.
 
   
 0.820
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.793
AEA42206.1
Hypothetical protein.
       0.543
AEA42207.1
KEGG: chu:CHU_1610 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.543
AEA45141.1
InterPro IPR011630; KEGG: sli:Slin_2316 protein of unknown function DUF1599; PFAM: Protein of unknown function DUF1599; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1599).
  
     0.520
AEA44756.1
ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: dfe:Dfer_3564 hypothetical protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative uncharacterized protein; PFAM: BadF/BadG/BcrA/BcrD ATPase family.
 
    0.498
AEA44379.1
Ferredoxin; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterPro IPR008333:IPR001433:IPR001041; KEGG: fjo:Fjoh_1048 ferredoxin; PFAM: Ferredoxin; Oxidoreductase, FAD-binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Flavodoxin reductase (Ferredoxin-NADPH reductase) family 1; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
  
 0.493
Your Current Organism:
Fluviicola taffensis
NCBI taxonomy Id: 755732
Other names: CFB group bacterium RW262, F. taffensis DSM 16823, Fluviicola taffensis DSM 16823, Fluviicola taffensis RW262, Fluviicola taffensis str. DSM 16823, Fluviicola taffensis strain DSM 16823
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