Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEA42209.1Mandelate racemase/muconate lactonizing protein; COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013342; KEGG: gfo:GFO_2310 O-succinylbenzoate synthase; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; SPTR: Chloromuconate cycloisomerase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; TIGRFAM: o-succinylbenzoic acid (OSB) synthetase. (344 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.948
AEA45351.1
O-succinylbenzoate--CoA ligase; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; KEGG: fps:FP1601 O-succinylbenzoate--CoA ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
  
 0.918
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.862
AEA42287.1
Chorismate binding domain-containing protein; COGs: COG1169 Isochorismate synthase; InterPro IPR015890; KEGG: zpr:ZPR_1714 isochorismate synthase; PFAM: Chorismate binding, C-terminal; SPTR: Isochorismate synthase; PFAM: chorismate binding enzyme.
 
   
 0.826
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.806
AEA42206.1
Hypothetical protein.
       0.543
AEA42207.1
KEGG: chu:CHU_1610 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.543
AEA44756.1
ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: dfe:Dfer_3564 hypothetical protein; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative uncharacterized protein; PFAM: BadF/BadG/BcrA/BcrD ATPase family.
 
    0.524
AEA45141.1
InterPro IPR011630; KEGG: sli:Slin_2316 protein of unknown function DUF1599; PFAM: Protein of unknown function DUF1599; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1599).
  
     0.520
AEA42201.1
COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR013708:IPR006151; KEGG: cat:CA2559_06730 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; PRIAM: Shikimate dehydrogenase; SPTR: Shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding domain; TIGRFAM: shikimate 5-dehydrogenase.
 
   
 0.500
Your Current Organism:
Fluviicola taffensis
NCBI taxonomy Id: 755732
Other names: CFB group bacterium RW262, F. taffensis DSM 16823, Fluviicola taffensis DSM 16823, Fluviicola taffensis RW262, Fluviicola taffensis str. DSM 16823, Fluviicola taffensis strain DSM 16823
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