Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEA43997.1Amidophosphoribosyltransferase; COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR000583; KEGG: zpr:ZPR_0274 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; PFAM: Glutamine amidotransferases class-II. (633 aa)    
Predicted Functional Partners:
purD
COGs: COG0151 Phosphoribosylamine-glycine ligase; HAMAP: Phosphoribosylglycinamide synthetase; InterPro IPR020562:IPR020561:IPR020560:IPR000115; KEGG: fjo:Fjoh_1041 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Putative uncharacterized protein; TIGRFAM: Phosphoribosylglycinamide synthetase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-g [...]
 0.998
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
  
 
 0.993
purH
Phosphoribosylaminoimidazolecarboxamideformyltra nsferase; COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982:IPR011607; KEGG: fjo:Fjoh_1459 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; MGS-like; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPC [...]
 
 
 0.993
AEA44322.1
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR000362:IPR013539; KEGG: gfo:GFO_1092 adenylosuccinate lyase; PFAM: Adenylosuccinate lyase C-terminal; Fumarate lyase; PRIAM: Adenylosuccinate lyase; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.990
purK
5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
 
 0.987
AEA44086.1
Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR010918; KEGG: cpi:Cpin_6522 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Putative phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, C-terminal domain.
 
  
 0.984
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: fjo:Fjoh_0369 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthetase, small subunit; TIGRFAM: Carbamoyl phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; [...]
 
 
 0.972
purC
COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; HAMAP: SAICAR synthetase; InterPro IPR001636; KEGG: fjo:Fjoh_2728 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
 
 
 0.972
AEA45801.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR006275:IPR005481:IPR005479:IPR005480; KEGG: fbc:FB2170_13823 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; PFAM: Carbamoyl-phosphate synthase L c [...]
  
 
 0.970
AEA42231.1
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR003806; KEGG: pcu:pc1568 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase family; ATP-grasp domain.
  
 
 0.965
Your Current Organism:
Fluviicola taffensis
NCBI taxonomy Id: 755732
Other names: CFB group bacterium RW262, F. taffensis DSM 16823, Fluviicola taffensis DSM 16823, Fluviicola taffensis RW262, Fluviicola taffensis str. DSM 16823, Fluviicola taffensis strain DSM 16823
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.