STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA44782.1InterPro IPR003749:IPR010035; KEGG: fps:FP0427 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (71 aa)    
Predicted Functional Partners:
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
AEA44784.1
COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: fjo:Fjoh_1602 thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI.
 
  
 0.944
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.937
AEA44785.1
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749; KEGG: fjo:Fjoh_1601 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
 
    0.934
AEA44789.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: fps:FP0434 molybdopterin and thiamine biosynthesis protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: Molybdopterin and thiamine biosynthesis protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
 
 0.924
AEA44788.1
Tyrosine lyase ThiH; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR012726; KEGG: fjo:Fjoh_1598 thiazole biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SPTR: Thiazole biosynthesis protein ThiH; TIGRFAM: Thiazole biosynthesis ThiH; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
 
  
 0.917
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.899
AEA44971.1
KEGG: mpt:Mpe_A2369 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.850
AEA45716.1
Galanin; KEGG: pmf:P9303_21011 galanin; SPTR: Possible Galanin; PFAM: Protein of unknown function (DUF3137).
  
  
 0.682
AEA46030.1
Galanin; KEGG: pmt:PMT0253 galanin; SPTR: Possible Galanin; PFAM: Protein of unknown function (DUF3137).
  
  
 0.682
Your Current Organism:
Fluviicola taffensis
NCBI taxonomy Id: 755732
Other names: CFB group bacterium RW262, F. taffensis DSM 16823, Fluviicola taffensis DSM 16823, Fluviicola taffensis RW262, Fluviicola taffensis str. DSM 16823, Fluviicola taffensis strain DSM 16823
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