STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY57717.1Formaldehyde-activating enzyme; COGs: COG1795 conserved hypothetical protein; InterPro IPR014826; KEGG: plm:Plim_1285 formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme; SPTR: Formaldehyde-activating enzyme; TIGRFAM: Formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); TIGRFAM: formaldehyde-activating enzyme. (165 aa)    
Predicted Functional Partners:
ADY57718.1
InterPro IPR015259: IPR005097; KEGG: psl:Psta_2659 methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Methylene-tetrahydromethanopterin dehydrogenase, N-terminal; Saccharopine dehydrogenase / Homospermidine synthase; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: MtdA bifunctional protein; PFAM: Methylene-tetrahydromethanopterin dehydrogenase, N-terminal.
 
  
 0.988
ffsA
Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
  
 0.979
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.914
ADY57716.1
ATP-grasp fold domain protein, DUF201-type; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase; InterPro IPR003806; KEGG: psl:Psta_2471 protein of unknown function DUF201; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein; PFAM: ATP-grasp domain.
 
   
 0.863
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
   
 0.836
ADY60267.1
COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: psl:Psta_4265 triphosphoribosyl-dephospho-CoA protein; PFAM: Triphosphoribosyl-dephospho-CoA protein; SPTR: Triphosphoribosyl-dephospho-CoA protein; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase.
 
   
 0.802
ADY61100.1
GHMP kinase domain protein; COGs: COG1907 sugar kinase; InterPro IPR013750; KEGG: mca:MCA2861 GHMP family kinase; PFAM: GHMP kinase, C-terminal; SPTR: Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinases C terminal; TIGRFAM: beta-RFAP synthase.
 
     0.801
ADY62215.1
COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR002489: IPR017550; KEGG: psl:Psta_0060 formylmethanofuran dehydrogenase subunit C; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: Molybdenum formylmethanofuran dehydrogenase, subunit C; TIGRFAM: Formylmethanofuran dehydrogenase subunit C; PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C.
 
     0.793
ADY59201.1
Hypothetical protein; COGs: COG1029 Formylmethanofuran dehydrogenase subunit B; KEGG: psl:Psta_1617 formylmethanofuran dehydrogenase subunit B-like protein; SPTR: Formylmethanofuran dehydrogenase subunit B.
 
     0.792
ADY60430.1
COGs: COG1229 Formylmethanofuran dehydrogenase subunit A; InterPro IPR013108: IPR012027; KEGG: plm:Plim_1687 formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; SPTR: DNA/RNA non-specific endonuclease; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A; PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A.
 
     0.792
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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