STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY57963.1COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: plm:Plim_2024 chorismate mutase; PFAM: Chorismate mutase, AroH class; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroH class; PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1. (123 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.957
ADY62369.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR020822: IPR001086: IPR002912; KEGG: plm:Plim_2048 prephenate dehydratase; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: P-protein (PheA); PFAM: Prephenate dehydratase; Chorismate mutase type II.
    
 0.939
ADY60378.1
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: psl:Psta_1058 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Cyclohexadienyl dehydrogenase; PFAM: Prephenate dehydrogenase.
  
 
  0.930
ADY58084.1
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR006221: IPR000991; KEGG: plm:Plim_0052 glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
    
  0.909
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
    
  0.907
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136: IPR000623: IPR011994; KEGG: plm:Plim_0331 cytidylate kinase; PFAM: Cytidylate kinase domain; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; PFAM: Cytidylate kinase; Shikimate kinase; TIGRFAM: cytidylate kinase.
      0.879
ADY58206.1
CutA1 divalent ion tolerance protein; COGs: COG1324 conserved hypothetical protein involved in tolerance to divalent cations; InterPro IPR004323; KEGG: dal:Dalk_3429 CutA1 divalent ion tolerance protein; PFAM: Divalent ion tolerance protein, CutA1; SPTR: CutA1 divalent ion tolerance protein; PFAM: CutA1 divalent ion tolerance protein.
    
   0.825
ADY59975.1
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890; KEGG: plm:Plim_2036 anthranilate synthase; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase component I; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade.
    
  0.815
mqnA
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
    
  0.812
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
  
  
 0.572
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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