STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepACytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (489 aa)    
Predicted Functional Partners:
ADY61856.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: gau:GAU_2335 gamma-glutamyltranspeptidase precursor; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase; TIGRFAM: Gamma-glutamyltranspeptidase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
 0.917
ADY62351.1
COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859; KEGG: plm:Plim_3256 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.830
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.829
ADY61533.1
L-aspartate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: plm:Plim_0135 aminotransferase class I and II; PFAM: Aminotransferase, class I/II; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
   
  0.811
ADY62151.1
Domain of unknown function DUF1745; COGs: COG4398 conserved hypothetical protein; InterPro IPR013702: IPR019494; KEGG: plm:Plim_1400 domain of unknown function DUF1745; PFAM: FIST domain, N-terminal; FIST C domain; SPTR: Putative uncharacterized protein; PFAM: FIST C domain; FIST N domain.
 
      0.507
ADY59892.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.464
ADY59177.1
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: cyt:cce_4584 putative Na+/H+ antiporter; PFAM: Cation/H+ exchanger; SPTR: Putative Na+/H+ antiporter; PFAM: Sodium/hydrogen exchanger family.
       0.459
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
     0.453
ADY60481.1
BRCT domain protein; COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterPro IPR019734: IPR001357: IPR000551: IPR001440; KEGG: plm:Plim_2188 tetratricopeptide TPR_2 repeat protein; PFAM: BRCT; HTH transcriptional regulator, MerR; Tetratricopeptide TPR-1; SPTR: Probable O-linked GlcNAc transferase; PFAM: Tetratricopeptide repeat; BRCA1 C Terminus (BRCT) domain.
 
  
 0.424
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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