STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY59826.1Universal protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: plm:Plim_1236 peptidase M22 glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22 glycoprotease; TIGRFAM: universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ. (231 aa)    
Predicted Functional Partners:
ADY60434.1
Uncharacterized protein family UPF0079, ATPase; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: plm:Plim_0814 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family.
 
 
 0.975
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.958
ADY60377.1
Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
  
 0.693
ADY61266.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR003142: IPR004408; KEGG: psl:Psta_2727 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Biotin protein ligase, C-terminal; SPTR: Biotin [acetyl-CoA-carboxylase] ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
   
    0.574
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
     0.559
ADY58296.1
Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122: IPR005273; KEGG: plm:Plim_0200 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like; SPTR: DNA polymerase, bacteriophage-type; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
  
    0.527
ADY60879.1
Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122: IPR005273; KEGG: rba:RB3915 putative DNA polymerase related protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Putative DNA polymerase related protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; manually curated; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
  
    0.527
ADY61572.1
COGs: COG0456 Acetyltransferase; InterPro IPR006464: IPR000182; KEGG: plm:Plim_1165 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Probable ribosomal-protein-alanine acetyltransferase; TIGRFAM: Ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase.
 
 
 0.519
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
  
 0.514
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
    0.460
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
Server load: low (20%) [HD]