STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY60846.1COGs: COG0369 Sulfite reductase alpha subunit (flavoprotein); InterPro IPR007202: IPR003097: IPR001433; KEGG: rba:RB380 sulfite reductase; PFAM: FAD-binding, type 1; Putative Fe-S cluster; Oxidoreductase FAD/NAD(P)-binding; PRIAM: NADPH--hemoprotein reductase; SPTR: Sulfite reductase [NADPH] flavoprotein alpha-component; PFAM: Putative Fe-S cluster; FAD binding domain; Oxidoreductase NAD-binding domain; TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha-component. (521 aa)    
Predicted Functional Partners:
ADY57942.1
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067; KEGG: plm:Plim_2758 sulfite reductase (NADPH); PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; PRIAM: Sulfite reductase (ferredoxin); SPTR: Sulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
 0.997
ADY60848.1
Nitrate reductase (quinol-dependent), catalytic subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006963: IPR006656: IPR006657; KEGG: scl:sce8491 nitrate reductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase, Fe4S4 domain; Molydopterin dinucleotide-binding domain; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.988
ADY60847.1
NAD(P)H-dependent nitrite reductase catalytic subunit; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067: IPR012798; KEGG: plm:Plim_3055 precorrin-3B synthase; PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; PRIAM: Ferredoxin--nitrite reductase; SPTR: Precorrin-3B synthase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobG-like; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: precorrin-3B synthase.
 
 
 0.978
ADY60500.1
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
 
 
 0.976
ADY62351.1
COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859; KEGG: plm:Plim_3256 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.976
ADY61949.1
COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: plm:Plim_0611 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase.
  
 
 0.932
ADY59892.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 0.925
ADY61714.1
COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: plm:Plim_2817 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; PFAM: Rhodanese-like domain.
    
 0.920
ADY60095.1
COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027; KEGG: psl:Psta_0464 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 0.916
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.916
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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