STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY61081.1ABC transporter related protein; COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003439; KEGG: rba:RB10876 excinuclease ABC subunit A; PFAM: ABC transporter-like; SPTR: Excinuclease ABC subunit A; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit. (861 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.986
ADY57650.1
UvrA family protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
  
 
0.919
ADY60420.1
ABC transporter related protein; COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003593: IPR003439; KEGG: nde:NIDE0568 excinuclease ABC subunit A; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Excinuclease ABC subunit A; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit.
  
  
 
0.918
ADY58010.1
Excinuclease ABC C subunit domain protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 
 0.821
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
   
 
 0.804
ADY59845.1
Chromosomal replication initiator DnaA domain protein; COGs: COG0593 ATPase involved in DNA replication initiation; InterPro IPR013159: IPR013317; KEGG: plm:Plim_3410 chromosomal replication initiator DnaA domain protein; PFAM: Chromosomal replication initiator, DnaA C-terminal; Chromosomal replication control, initiator (DnaA)/regulator (Hda); SMART: Chromosomal replication initiator, DnaA C-terminal; SPTR: Chromosomal replication initiation protein; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA.
  
   
 0.585
ADY61082.1
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
       0.545
ADY59730.1
COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623: IPR002939; KEGG: psl:Psta_4209 chaperone DnaJ domain protein; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ-like protein; PFAM: DnaJ C terminal region; DnaJ domain; TIGRFAM: chaperone protein DnaJ.
  
 
 0.516
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
   
 0.514
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
  
 0.500
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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