STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY61550.1Purine or other phosphorylase family 1; InterPro IPR000845; KEGG: rpd:RPD_3572 hypothetical protein; PFAM: Nucleoside phosphorylase; SPTR: Purine and other phosphorylase, family 1; manually curated; PFAM: Phosphorylase superfamily. (262 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.918
ADY59752.1
COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: plm:Plim_1904 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: Hopene cyclase; Squalene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase.
 
   
 0.778
ADY59962.1
Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: plm:Plim_3361 hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM; SPTR: Fe-S protein, radical SAM family; TIGRFAM: Hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH.
 
   
 0.778
yacG
UPF0243 zinc-binding protein yacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
       0.773
ADY61552.1
Regulatory protein, FmdB family; COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: plm:Plim_2923 regulatory protein, FmdB family; PFAM: Regulatory protein, FmdB, putative; SPTR: Putative uncharacterized protein; TIGRFAM: Regulatory protein, FmdB, putative; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
       0.727
ADY58659.1
COGs: COG1033 exporter of the RND superfamily protein; KEGG: plm:Plim_3348 hopanoid biosynthesis associated RND transporter like protein HpnN; SPTR: Putative rRNA methylase; PFAM: MMPL family.
 
     0.575
ADY61549.1
KEGG: npu:Npun_F5232 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.545
ADY60481.1
BRCT domain protein; COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterPro IPR019734: IPR001357: IPR000551: IPR001440; KEGG: plm:Plim_2188 tetratricopeptide TPR_2 repeat protein; PFAM: BRCT; HTH transcriptional regulator, MerR; Tetratricopeptide TPR-1; SPTR: Probable O-linked GlcNAc transferase; PFAM: Tetratricopeptide repeat; BRCA1 C Terminus (BRCT) domain.
 
  
 0.530
ADY57981.1
KEGG: plm:Plim_2454 hypothetical protein; SPTR: Tetratricopeptide repeat protein.
  
     0.487
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.485
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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