STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rphRNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (245 aa)    
Predicted Functional Partners:
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.979
ADY58071.1
COGs: COG0349 Ribonuclease D; InterPro IPR002562: IPR002121; KEGG: plm:Plim_0672 ribonuclease D; PFAM: 3'-5' exonuclease; Helicase/RNase D C-terminal, HRDC domain; PRIAM: Ribonuclease D; SMART: 3'-5' exonuclease; Helicase/RNase D C-terminal, HRDC domain; SPTR: Ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D.
   
 0.977
ADY58167.1
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
    0.966
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
 
 0.855
rpsD
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  0.820
ADY59254.1
NUDIX hydrolase; InterPro IPR000086; KEGG: amu:Amuc_0001 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: MutT-like protein; PFAM: NUDIX domain.
    
 0.808
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 0.775
ADY57647.1
COGs: COG1643 HrpA-like helicase; InterPro IPR001650: IPR007502: IPR011709: IPR014001: IPR 003593: IPR010222; KEGG: nhl:Nhal_1290 ATP-dependent helicase HrpA; PFAM: Helicase-associated domain; DNA/RNA helicase, C-terminal; Domain of unknown function DUF1605; SMART: DEAD-like helicase, N-terminal; ATPase, AAA+ type, core; DNA/RNA helicase, C-terminal; SPTR: ATP-dependent helicase HrpA; TIGRFAM: RNA helicase, ATP-dependent DEAH box, HrpA type; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DU [...]
    
 0.770
ADY58474.1
COGs: COG0539 Ribosomal protein S1; InterPro IPR003029: IPR018032; KEGG: plm:Plim_1620 ribosomal protein S1; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: 30S ribosomal protein S1; TIGRFAM: Ribosomal S1 synthesis/modification protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
   
  0.667
ADY61599.1
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR003029; KEGG: plm:Plim_3572 RNA binding S1 domain protein; PFAM: Ribosomal protein S1, RNA binding domain; SPTR: 30S ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
   
  0.667
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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