STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY61949.1COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: plm:Plim_0611 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: O-succinylhomoserine (thiol)-lyase. (386 aa)    
Predicted Functional Partners:
ADY62351.1
COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859; KEGG: plm:Plim_3256 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.987
ADY59892.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.980
ADY57742.1
COGs: COG2040 Homocysteine/selenocysteine methylase (S-methylmethionine-dependent); InterPro IPR003726; KEGG: scl:sce0497 putative homocysteine S-methyltransferase family protein; PFAM: Homocysteine S-methyltransferase; SPTR: Putative homocysteine S-methyltransferase family protein; PFAM: Homocysteine S-methyltransferase.
 
 
 0.938
ADY58685.1
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR000277: IPR006235; KEGG: plm:Plim_4098 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
 
0.935
ADY60846.1
COGs: COG0369 Sulfite reductase alpha subunit (flavoprotein); InterPro IPR007202: IPR003097: IPR001433; KEGG: rba:RB380 sulfite reductase; PFAM: FAD-binding, type 1; Putative Fe-S cluster; Oxidoreductase FAD/NAD(P)-binding; PRIAM: NADPH--hemoprotein reductase; SPTR: Sulfite reductase [NADPH] flavoprotein alpha-component; PFAM: Putative Fe-S cluster; FAD binding domain; Oxidoreductase NAD-binding domain; TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha-component.
  
 
 0.932
ADY57942.1
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067; KEGG: plm:Plim_2758 sulfite reductase (NADPH); PFAM: Nitrite/sulphite reductase 4Fe-4S domain; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; PRIAM: Sulfite reductase (ferredoxin); SPTR: Sulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
  
 0.930
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
   
 0.930
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.926
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.916
ADY61113.1
Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: psl:Psta_1544 aminotransferase class IV; PFAM: Aminotransferase, class IV; SPTR: Branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV.
   
 0.916
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
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