STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADY62228.1Transketolase central region; COGs: COG0021 Transketolase; InterPro IPR005475: IPR005476; KEGG: cyc:PCC7424_4061 transketolase domain protein; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain. (640 aa)    
Predicted Functional Partners:
ADY59146.1
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: plm:Plim_3832 transaldolase; PFAM: Transaldolase; SPTR: Transaldolase; PFAM: Transaldolase; TIGRFAM: transaldolase, mycobacterial type.
  
 0.919
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.872
ADY59938.1
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  
 
 0.807
ADY59392.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR006424: IPR020828: IPR020829; KEGG: plm:Plim_0647 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; manually curated; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain [...]
  
 0.764
ADY60016.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: plm:Plim_0648 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
  
 0.720
ADY61129.1
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: psl:Psta_2907 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase.
  
 
 0.694
ADY58611.1
COGs: COG3236 conserved hypothetical protein; InterPro IPR012816; KEGG: bph:Bphy_3371 hypothetical protein; PFAM: Conserved hypothetical protein CHP02464; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1768); TIGRFAM: conserved hypothetical protein, ribA/ribD-fused.
  
     0.679
pgk
COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: rba:RB10500 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.660
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.639
ADY58088.1
COGs: COG0469 Pyruvate kinase; InterPro IPR001697: IPR015793: IPR015794; KEGG: plm:Plim_3274 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.572
Your Current Organism:
Rubinisphaera brasiliensis
NCBI taxonomy Id: 756272
Other names: Planctomyces brasiliensis ATCC 49424, Planctomyces brasiliensis DSM 5305, Planctomyces brasiliensis str. DSM 5305, Planctomyces brasiliensis strain DSM 5305, R. brasiliensis DSM 5305, Rubinisphaera brasiliensis DSM 5305
Server load: high (94%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.