Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFM01621.1PFAM: Uroporphyrinogen decarboxylase (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (381 aa)    
Predicted Functional Partners:
AFM01618.1
PFAM: Protein of unknown function (DUF1638).
 
     0.893
AFM01622.1
Putative cobalamin binding protein; PFAM: B12 binding domain.
 
    0.872
AFM01619.1
PFAM: Pterin binding enzyme.
 
   
 0.856
AFM01616.1
PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
 
     0.848
AFM00437.1
PFAM: Protein of unknown function (DUF1638).
 
     0.772
AFM01620.1
Hypothetical protein.
       0.746
AFM01965.1
PFAM: Protein of unknown function (DUF1638).
 
     0.733
AFM00520.1
Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily.
  
     0.673
AFM02212.1
PFAM: Predicted metal-binding protein (DUF2284).
 
     0.665
AFM00440.1
PFAM: Predicted metal-binding protein (DUF2284).
  
     0.650
Your Current Organism:
Desulfitobacterium dehalogenans
NCBI taxonomy Id: 756499
Other names: D. dehalogenans ATCC 51507, Desulfitobacterium dehalogenans ATCC 51507, Desulfitobacterium dehalogenans DSM 9161, Desulfitobacterium dehalogenans JW/IU-DC1, Desulfitobacterium dehalogenans str. ATCC 51507, Desulfitobacterium dehalogenans strain ATCC 51507
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