Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEN04505.1PFAM: Prephenate dehydrogenase; KEGG: hla:Hlac_1779 prephenate dehydrogenase. (256 aa)    
Predicted Functional Partners:
AEN06775.1
KEGG: hla:Hlac_0264 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT.
 
 
 0.974
AEN06184.1
Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II.
 
 
 0.962
hisC
PFAM: Aminotransferase, class I/II; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: hvo:HVO_1295 histidinol-phosphate aminotransferase.
 
  
 0.924
AEN04504.1
PFAM: Methyltransferase type 12; KEGG: hbo:Hbor_19120 methyltransferase family protein.
 
     0.922
AEN07259.1
Aspartate transaminase; KEGG: hla:Hlac_0930 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
  
  
  0.914
AEN04531.1
KEGG: hbo:Hbor_21520 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II.
    
 0.911
AEN04749.1
Aspartate transaminase; KEGG: htu:Htur_1170 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
    
 0.911
AEN05304.1
KEGG: hbo:Hbor_16150 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II.
    
 0.911
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.592
AEN07106.1
PFAM: Asparagine synthase; KEGG: hbo:Hbor_22320 asparagine synthase (glutamine-hydrolyzing).
     
 0.563
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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