Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN04513.1PFAM: Protein of unknown function DUF151; KEGG: hla:Hlac_0858 protein of unknown function DUF151. (144 aa)    
Predicted Functional Partners:
hisE
TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphatase; KEGG: nph:NP0470A phosphoribosyl-ATP pyrophosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase.
       0.708
AEN04514.1
Protein of unknown function DUF555; PFAM: Uncharacterised protein family UPF0212; KEGG: htu:Htur_2443 protein of unknown function DUF555.
       0.551
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.461
AEN06916.1
KEGG: hut:Huta_0325 preprotein translocase subunit SecG.
       0.446
AEN05217.1
TraB determinant protein; PFAM: Pheromone shutdown-related, TraB; KEGG: hvo:HVO_1554 TraB family protein.
       0.428
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (6%) [HD]