Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN04517.1PFAM: Mechanosensitive ion channel MscS; KEGG: hla:Hlac_1441 mechanosensitive ion channel. (264 aa)    
Predicted Functional Partners:
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
 
   
 0.935
AEN04519.1
Protein of unknown function UPF0118; PFAM: Uncharacterised protein family UPF0118; KEGG: hma:rrnAC3369 hypothetical protein.
 
    0.630
AEN04779.1
NMD3 family protein; PFAM: NMD3; KEGG: hbo:Hbor_01210 nmd protein affecting ribosome stability and mRNA decay.
  
    0.580
AEN06733.1
TIGRFAM: Pyruvate kinase; KEGG: hma:rrnAC0546 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family.
  
  
 0.438
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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