Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fbpKEGG: hla:Hlac_2458 fructose-1,6-bisphosphatase; HAMAP: Fructose-1,6-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (286 aa)    
Predicted Functional Partners:
AEN04522.1
PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hje:HacjB3_11450 fructose-bisphosphate aldolase.
    
 0.989
pgi
KEGG: hbo:Hbor_05630 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.934
aroA
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.923
AEN04523.1
KEGG: hvo:HVO_1445 hypothetical protein.
       0.800
gap
PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type II; HAMAP: Glyceraldehyde-3-phosphate dehydrogenase; KEGG: htu:Htur_0284 glyceraldehyde-3-phosphate dehydrogenase, type II.
  
  
 0.753
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
  
 0.657
AEN04524.1
KEGG: hbo:Hbor_17950 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal.
  
  
 0.596
AEN06733.1
TIGRFAM: Pyruvate kinase; KEGG: hma:rrnAC0546 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family.
  
  
 0.569
AEN06503.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: hsl:OE3634F isocitrate dehydrogenase (NADP); PFAM: Isocitrate/isopropylmalate dehydrogenase.
   
  
 0.540
AEN07018.1
KEGG: hvo:HVO_2588 isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase.
   
  
 0.540
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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