| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN04531.1 | pyrB | Halar_0760 | Halar_1361 | KEGG: hbo:Hbor_21520 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: hvo:HVO_1454 aspartate carbamoyltransferase. | 0.904 |
| AEN04531.1 | ribH | Halar_0760 | Halar_0759 | KEGG: hbo:Hbor_21520 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.920 |
| AEN05034.1 | ribH | Halar_1288 | Halar_0759 | TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_22420 k+ transporter, NAD-binding component. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.884 |
| AEN05187.1 | AEN06519.1 | Halar_1451 | Halar_2888 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.923 |
| AEN05187.1 | AEN06554.1 | Halar_1451 | Halar_2924 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | PFAM: Dihydroorotate dehydrogenase, class 1/ 2; TIGRFAM: Dihydroorotate dehydrogenase, class 2; HAMAP: Dihydroorotate dehydrogenase; KEGG: hla:Hlac_0019 dihydroorotate dehydrogenase 2. | 0.445 |
| AEN05187.1 | AEN07265.1 | Halar_1451 | Halar_3691 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.979 |
| AEN05187.1 | ribH | Halar_1451 | Halar_0759 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.929 |
| AEN05187.1 | ribL | Halar_1451 | Halar_1172 | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.423 |
| AEN06519.1 | AEN05187.1 | Halar_2888 | Halar_1451 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 0.923 |
| AEN06519.1 | AEN07265.1 | Halar_2888 | Halar_3691 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 0.981 |
| AEN06519.1 | ribH | Halar_2888 | Halar_0759 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
| AEN06519.1 | ribL | Halar_2888 | Halar_1172 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.424 |
| AEN06554.1 | AEN05187.1 | Halar_2924 | Halar_1451 | PFAM: Dihydroorotate dehydrogenase, class 1/ 2; TIGRFAM: Dihydroorotate dehydrogenase, class 2; HAMAP: Dihydroorotate dehydrogenase; KEGG: hla:Hlac_0019 dihydroorotate dehydrogenase 2. | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 0.445 |
| AEN06554.1 | pyrB | Halar_2924 | Halar_1361 | PFAM: Dihydroorotate dehydrogenase, class 1/ 2; TIGRFAM: Dihydroorotate dehydrogenase, class 2; HAMAP: Dihydroorotate dehydrogenase; KEGG: hla:Hlac_0019 dihydroorotate dehydrogenase 2. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: hvo:HVO_1454 aspartate carbamoyltransferase. | 0.967 |
| AEN06554.1 | ribH | Halar_2924 | Halar_0759 | PFAM: Dihydroorotate dehydrogenase, class 1/ 2; TIGRFAM: Dihydroorotate dehydrogenase, class 2; HAMAP: Dihydroorotate dehydrogenase; KEGG: hla:Hlac_0019 dihydroorotate dehydrogenase 2. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.655 |
| AEN06554.1 | ribL | Halar_2924 | Halar_1172 | PFAM: Dihydroorotate dehydrogenase, class 1/ 2; TIGRFAM: Dihydroorotate dehydrogenase, class 2; HAMAP: Dihydroorotate dehydrogenase; KEGG: hla:Hlac_0019 dihydroorotate dehydrogenase 2. | Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.537 |
| AEN07265.1 | AEN05187.1 | Halar_3691 | Halar_1451 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | TIGRFAM: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; KEGG: hut:Huta_0543 5-amino-6-(5-phosphoribosylamino)uracil reductase; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal. | 0.979 |
| AEN07265.1 | AEN06519.1 | Halar_3691 | Halar_2888 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.981 |
| AEN07265.1 | ribH | Halar_3691 | Halar_0759 | Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; KEGG: hla:Hlac_0200 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| pyrB | AEN04531.1 | Halar_1361 | Halar_0760 | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: hvo:HVO_1454 aspartate carbamoyltransferase. | KEGG: hbo:Hbor_21520 aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase, class I/II. | 0.904 |