Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN04539.1PFAM: Protein of unknown function DUF357; KEGG: hla:Hlac_0959 protein of unknown function DUF357. (97 aa)    
Predicted Functional Partners:
AEN04538.1
Thioredoxin-disulfide reductase; KEGG: hla:Hlac_0323 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.735
AEN06168.1
Hypothetical protein; Manually curated; KEGG: hut:Huta_0046 hypothetical protein.
  
     0.669
rpl39e
PFAM: Ribosomal protein L39e; KEGG: hwa:HQ3424A 50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family.
 
     0.653
AEN05448.1
UPF0179 protein; KEGG: hvo:HVO_2851 hypothetical protein; HAMAP: UPF0179 protein; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
 
     0.625
AEN04927.1
Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; KEGG: hbo:Hbor_21950 proteasome rpn11 subunit jamm motif protein.
 
     0.619
AEN06694.1
Transcriptional regulator, XRE family; HAMAP: HTH-type transcriptional regulatory protein; PFAM: Helix-turn-helix type 3; KEGG: hbo:Hbor_28330 transcriptional regulator, xre family; SMART: Helix-turn-helix type 3.
  
     0.619
AEN06981.1
SMART: ATPase, AAA+ type, core; TIGRFAM: Peptidase S16, archaeal lon homologues; KEGG: hwa:HQ1163A ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; Belongs to the peptidase S16 family.
  
     0.619
AEN05910.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: hma:rrnAC3263 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.592
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.591
AEN06687.1
KEGG: hla:Hlac_0818 translation initiation factor IF-2 subunit beta; PFAM: Translation initiation factor IF2/IF5; Deoxyribonuclease/rho motif-related TRAM; SMART: Translation initiation factor IF2/IF5.
  
     0.583
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.