Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN04568.1KEGG: hla:Hlac_0795 hypothetical protein. (115 aa)    
Predicted Functional Partners:
AEN07282.1
PFAM: Uncharacterised conserved protein UCP022079; KEGG: hla:Hlac_1933 hypothetical protein.
  
     0.722
AEN05424.1
PFAM: Bacterial transferase hexapeptide repeat; KEGG: hbo:Hbor_16110 acyltransferase.
  
     0.713
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...]
  
   
 0.709
AEN06602.1
PFAM: Protein of unknown function DUF460; KEGG: hbo:Hbor_29620 hypothetical protein.
  
     0.697
AEN06170.1
PFAM: Protein of unknown function DUF343; KEGG: hla:Hlac_0944 protein of unknown function DUF343.
  
     0.692
AEN06573.1
PFAM: Protein of unknown function DUF2072, Zinc-ribbon; KEGG: hvo:HVO_3012 hypothetical protein.
  
     0.690
AEN07266.1
KEGG: hvo:HVO_0422 hypothetical protein.
  
    0.664
AEN06856.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: hvo:HVO_0770 hypothetical protein.
 
     0.658
AEN05867.1
PFAM: Protein of unknown function DUF1610; KEGG: hla:Hlac_2340 protein of unknown function DUF1610.
  
     0.654
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
  
     0.646
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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