Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04626.1PFAM: Protein of unknown function DUF373; KEGG: hvo:HVO_0882 hypothetical protein. (373 aa)    
Predicted Functional Partners:
AEN04627.1
KEGG: hmu:Hmuk_2828 signal peptide peptidase SppA, 36K type; TIGRFAM: Peptidase S49, SppA; PFAM: Peptidase S49.
       0.778
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
 
     0.710
AEN05690.1
PUA domain containing protein; KEGG: hbo:Hbor_06070 tRNA-archaeosine synthase; PFAM: Pseudouridine synthase/archaeosine transglycosylase; Queuine/other tRNA-ribosyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
   
 0.680
AEN04628.1
KEGG: hla:Hlac_0452 hypothetical protein.
 
     0.676
AEN06641.1
PFAM: Radical SAM; KEGG: nmg:Nmag_1383 radical SAM domain protein.
 
     0.676
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.664
AEN05586.1
PFAM: Protein of unknown function DUF2240; KEGG: hvo:HVO_2372 hypothetical protein.
  
     0.649
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
     0.646
AEN06577.1
TIGRFAM: Peptidase S26B, eukaryotic signal peptidase; KEGG: hvo:HVO_0002 signal peptidase I.
  
     0.638
AEN04587.1
KEGG: hvo:HVO_1107 hypothetical protein; PFAM: Protein of unknown function DUF1119, archaea; SMART: Peptidase A22, presenilin signal peptide.
  
     0.619
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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