STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN04641.1PFAM: Heat shock protein Hsp20; KEGG: hla:Hlac_2381 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (117 aa)    
Predicted Functional Partners:
AEN04642.1
PFAM: ABC-1; KEGG: hbo:Hbor_07170 protein kinase.
       0.592
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.537
AEN04640.1
Transposase, IS605 OrfB family; KEGG: nph:NP3036A IS1341-type transposase; TIGRFAM: Transposase, IS605 OrfB, C-terminal; PFAM: Transposase, IS605 OrfB, C-terminal.
       0.494
AEN04643.1
Aspartate transaminase; KEGG: hla:Hlac_1580 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
  
    0.467
AEN06448.1
Molybdenum cofactor synthesis domain protein; KEGG: hbo:Hbor_07200 molybdopterin molybdochelatase; TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV.
       0.459
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.445
AEN04639.1
PFAM: Amidohydrolase 2; KEGG: hvo:HVO_B0105 amidohydrolase family superfamily.
       0.423
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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