Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04641.1PFAM: Heat shock protein Hsp20; KEGG: hla:Hlac_2381 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (117 aa)    
Predicted Functional Partners:
AEN06777.1
PFAM: Heat shock protein Hsp20; KEGG: hje:HacjB3_08020 HSP20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
AEN06778.1
PFAM: Heat shock protein Hsp20; KEGG: hvo:HVO_0451 HSP20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
AEN07270.1
PFAM: Heat shock protein Hsp20; KEGG: hvo:HVO_0482 HSP20-type molecular chaperone.
     
  0.900
AEN04642.1
PFAM: ABC-1; KEGG: hbo:Hbor_07170 protein kinase.
       0.845
AEN06447.1
KEGG: hla:Hlac_2122 molybdenum cofactor synthesis domain protein; TIGRFAM: Molybdenum cofactor synthesis; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV.
       0.685
AEN04643.1
Aspartate transaminase; KEGG: hla:Hlac_1580 aminotransferase class I and II; PFAM: Aminotransferase, class I/II.
  
    0.647
eif5a
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
     
 0.639
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.505
AEN04640.1
Transposase, IS605 OrfB family; KEGG: nph:NP3036A IS1341-type transposase; TIGRFAM: Transposase, IS605 OrfB, C-terminal; PFAM: Transposase, IS605 OrfB, C-terminal.
       0.494
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.456
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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