Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEN04648.1PFAM: Ribonuclease H; KEGG: hla:Hlac_0307 ribonuclease H. (197 aa)    
Predicted Functional Partners:
AEN06146.1
PFAM: Ribonuclease H; KEGG: htu:Htur_1544 ribonuclease H.
  
  
 
0.924
AEN04647.1
KEGG: hla:Hlac_0306 hypothetical protein.
       0.907
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
 0.829
tfb-3
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
       0.711
AEN06790.1
KEGG: hbo:Hbor_00410 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00268; PFAM: Asparagine synthase; tRNA methyl transferase-like.
 
      0.705
AEN04649.1
PFAM: Protein of unknown function DUF81; KEGG: hwa:HQ2283A hypothetical protein.
       0.551
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
   
 0.534
AEN04650.1
Protein of unknown function DUF650; Involved in DNA damage repair.
       0.520
AEN05865.1
PFAM: Dodecin flavoprotein; KEGG: hla:Hlac_2497 protein of unknown function DUF1458.
     
 0.453
AEN05881.1
PFAM: CRISPR-associated protein Cas4; KEGG: hvo:HVO_2767 ATP-dependent DNA helicase Dna2.
    
 
 0.422
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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