Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN04662.1TIGRFAM: Folate-binding, YgfZ; KEGG: hbo:Hbor_27940 aminomethyltransferase; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel. (367 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.998
AEN05767.1
KEGG: hbo:Hbor_08360 glycine dehydrogenase (decarboxylating) alpha subunit; PFAM: Glycine cleavage system P-protein, N-terminal.
 
 
 0.998
AEN05768.1
PFAM: Glycine cleavage system P-protein, N-terminal; KEGG: hbo:Hbor_08350 glycine dehydrogenase (decarboxylating) subunit beta.
 
 0.998
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.975
AEN06484.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: hbo:Hbor_02940 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
  
 0.948
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 0.940
AEN04576.1
Phosphoribosylglycinamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, formylation region; TIGRFAM: Phosphoribosylglycinamide formyltransferase; KEGG: hla:Hlac_0925 phosphoribosylglycinamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme, formylation region; Formyl transferase, N-terminal.
  
 
 0.937
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
  
 
0.927
AEN05352.1
Serine--pyruvate transaminase; KEGG: htu:Htur_1862 aminotransferase class V; PFAM: Aminotransferase, class V/Cysteine desulfurase.
  
 
 0.923
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
  
 0.922
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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